Synopsis of recent research by authors named "Alla Polozova"
- Alla Polozova's research primarily focuses on the characterization and optimization of therapeutic antibodies and biosimilars, specifically emphasizing their glycosylation patterns and the impact on functionality, such as antibody-dependent cell-mediated cytotoxicity (ADCC).
- Key findings suggest that modifications in glycan structures, such as increased afucosylation and terminal galactosylation, can significantly enhance the efficacy of IgG1 antibodies, which is crucial for their therapeutic applications.
- The author has also contributed to the understanding of subvisible particle analysis during biotherapeutic development, highlighting the importance of characterizing these particles to ensure the safety and efficacy of biopharmaceutical products.
