Objective: The features of сhronorhythmic alterations of excretory renal function under the physiological conditions of the pineal gland (PG) under the influence of a blockade of synthesis of nitrogen monoxide (NO) and melatonin correction were investigated. The aim: Aim of our work was to investigate circadian characteristic of kidney excretory function influenced by nitrogen monoxide synthesis blockade under conditions of pineal gland normal with peguliarities of melatonin effect.
Patients And Methods: Materials and methods: The experiments were conducted on 72 mature non-linear albino male rats with their body mass 0,15-0,18 kg.