Publications by authors named "Alkhateeb M"

Background: Artificial intelligence (AI) is set to shape the future of medical practice. The perspective and understanding of medical students are critical for guiding the development of educational curricula and training.

Objective: This study aims to assess and compare medical AI-related attitudes among medical students in general medicine and in one of the visually oriented fields (pathology), along with illuminating their anticipated role of AI in the rapidly evolving landscape of AI-enhanced health care.

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Introduction: Surgeon attire significantly affects patients' perceptions and can improve patient-surgeon relationships, which are crucial for patient comfort, experience, satisfaction, and treatment adherence. Understanding patient preferences for surgeon attire is essential, particularly in Saudi Arabia, for establishing appropriate dress codes in healthcare institutions. This national cross-sectional study aimed to fill this gap by assessing patient preferences for surgeon attire and its impact on patients' confidence in their surgeons across various medical settings.

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Objectives: The study aims to characterize BRCA1/2 mutations in Pakistani gastric cancer (GC) patients, identifying unique pathogenic variants and evaluating their potential as diagnostic biomarkers, while also exploring therapeutic avenues for personalized treatment strategies.

Methodology: In this study, we investigated the role of Breast Cancer gene 1 (BRCA1) and Breast Cancer gene 2 (BRCA2) mutations in Pakistani GC patients and their functional implications using Next-Generation Sequencing (NGS).

Results: Through NGS, we identified a total of 19 mutations in BRCA1 and 11 mutations in BRCA2, all with high mutation quality scores.

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Gastric cancer predominantly adenocarcinoma, accounts for over 85% of gastric cancer diagnoses. Current therapeutic options are limited, necessitating the discovery of novel drug targets and effective treatments. The Affymetrix gene expression microarray dataset (GSE64951) was retrieved from NCBI-GEO data normalization and DEGs identification was done by using R-Bioconductor package.

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Article Synopsis
  • - The study investigates using CRISPR-Cas9 technology to target and inhibit the mutant Androgen Receptor (AR) gene responsible for spinal bulbar muscular atrophy (SBMA), a neurodegenerative disorder.
  • - Researchers designed specific guided RNAs (gRNAs) targeting the AR gene that show high efficiency, accurate matching, and minimal off-target effects, suggesting they could be effective for gene editing.
  • - The findings indicate a promising potential for CRISPR-Cas9 as a therapeutic option for SBMA, advocating for further research to evaluate its effectiveness in preclinical and clinical settings.
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Aim: To evaluate (1) Audiological and surgical outcomes in patients with otosclerosis following cochlear implantation. (2) surgical difficulties and outcomes between both groups. (3) Audiological outcomes between both groups.

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Cervical cancer is a significant health concern for women worldwide, with human papillomavirus (HPV) being the primary cause. This study aimed to assess Saudi women's awareness and knowledge of HPV, determine their information sources, and evaluate their intention to receive the HPV vaccine. A questionnaire-based survey was conducted among 654 Saudi females aged 18 to 60 years from January to May 2023.

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Microalgae-mediated nanoparticle (NP) biosynthesis is a promising green synthesis method that overcomes the challenges of conventional synthesis methods. The novel strain CCAP 6006/5 was isolated, purified, and characterized morphologically and genetically. GC-MS analysis of the algal biomass (D) phytochemicals showed the abundance for elaidic acid (18.

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: to identify advanced or "so-called inoperable" cases of tympanojugular paragangliomas (PGLs) and analyze how each case is surgically managed and followed afterward. : a retrospective case series study. Out of 262 type C and D TJPs and more than 10 cases of advanced or so-called inoperable cases, files of 6 patients with a diagnosis of advanced tympanojugular PGLs who were referred to an otology and skull-base center between 1996 and 2021 were reviewed to analyze management and surgical outcomes.

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The number of birds or their total live weight in relation to a given area is known as stocking density; higher stocking densities will cause more stress to the birds, which may have an impact on their physiological state, productivity, carcass quality, growth performance, immunity, metabolism, and meat quality. The present study aimed to investigate the potential impact of 2 different stocking densities on growth performance, carcass characteristics, meat quality, serum, and expression of Insulin like growth factor-1 (IGF-1), muscle regulatory genes expression and serum biochemical indicators of broilers supplemented with essential oils (EO). In total, 784-day-old chicks of Ross 308 were randomly assigned into 4 different groups with 7 replicates for each: Normal feed (no essential oils [EO] added) and normal stocking as 9 bird/m, (NSD).

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The demand for strengthening reinforced concrete (RC) structures has increased considerably. Implementing carbon-fiber-reinforced polymer (CFRP) bars and concrete jacketing are the most effective techniques for RC beam retrofitting. Using the mechanical anchorage system (MAS) to attach CFRP bars to old concrete is highly recommended to avoid any debonding when it is applied to cyclic loads.

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Article Synopsis
  • Children in Jordan show high levels of anti-S and anti-N antibodies against COVID-19, indicating strong immune responses, especially in those over 12 years old.
  • A study involving 151 unvaccinated children revealed that a majority tested positive for these antibodies, with older children exhibiting higher concentrations than younger ones.
  • Overall, while children's anti-S levels were found to be higher than those of naturally infected unvaccinated adults, adults had significantly greater anti-N antibody levels, suggesting different immune response dynamics across age groups.
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Asiatic acid (AA) is a polyphenolic compound with potent antioxidative and anti-inflammatory activities that make it a potential choice to attenuate inflammation and oxidative insults associated with ulcerative colitis (UC). Hence, the present study aimed to evaluate if AA can attenuate molecular, biochemical, and histological alterations in the acetic acid-induced UC model in rats. To perform the study, five groups were applied, including the control, acetic acid-induced UC, UC-treated with 40 mg/kg aminosalicylate (5-ASA), UC-treated with 20 mg/kg AA, and UC-treated with 40 mg/kg AA.

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Background: Epilepsy frequently accompanies Major Depressive Disorder (MDD). Notably, people with temporal lobe epilepsy and hippocampal sclerosis may face an increased susceptibility to MDD, as evidence indicates the involvement of the limbic system in the development of emotional symptoms.

Objectives: To determine the prevalence and predictors of depression in temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) and compare them to those of other epilepsy types.

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Esculeoside A (ESA) is a tomato-derived glycoside with antioxidant and anti-inflammatory properties. The protective effect of ESA against diabetic retinopathy is not well-investigated and was the core objective of this study. In addition, we tested if such protection involves the activation of Nrf2 signaling.

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Article Synopsis
  • The study aimed to analyze trends in Antiseizure Medication (ASM) use and the frequency of Psychogenic Non-Epileptic Seizures (PNES) in patients with and without concurrent epileptic seizures.
  • A review of 145 patients indicated that those with just PNES had a higher likelihood of reducing or stopping ASMs compared to those with both PNES and epilepsy, especially noticeable over several years of follow-up.
  • While both groups showed initial reductions in PNES spells, the long-term outcomes revealed fluctuating patterns, with no significant difference in spell frequency reduction between the two groups at the final follow-up point.
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Article Synopsis
  • Wheat has higher crude protein and amino acids than corn but contains anti-nutritional factors that can negatively affect ruminant digestion.
  • The study examined how replacing corn with different percentages of wheat affects liver metabolism in Tibetan lambs over 130 days.
  • Results showed that a 10% wheat diet improved immune markers and altered liver cell arrangements compared to higher wheat diets, along with significant changes in gene expression related to various biological pathways.
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Background: Early identification of a patient with infection who may develop sepsis is of utmost importance. Unfortunately, this remains elusive because no single clinical measure or test can reflect complex pathophysiological changes in patients with sepsis. However, multiple clinical and laboratory parameters indicate impending sepsis and organ dysfunction.

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Background And Objectives: Psychogenic non-epileptic seizures (PNES) are commonly associated with co-existing psychiatric disorders. The relationship between psychiatric factors and PNES episodes with and without epilepsy remains understudied. We reviewed co-existing psychiatric disorders in PNES-only, PNES with epilepsy aiming to examine whether these co-existing disorders associated with PNES clinical presentation and long-term outcomes.

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Background And Objectives: Although penetrative sex is the most common route of HPV infection, there is strong evidence of non-sexual modes of transmission. As the first of its kind, this study aimed to investigate the knowledge and awareness of Jordanian physicians on such routes.

Methods: A questionnaire was conducted among a national Jordanian sample of physicians from Jordanian health sectors.

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The long-term immunoglobulin responses of COVID-19 vaccinations is important to determine the efficacy of these vaccinations. This study aimed to investigate and compare the long-term immunoglobulin response of COVID-19 vaccination recipients, using anti-S IgG, anti-N IgG, and IgM titer levels. This study included 267 participants, comprising individuals who tested positive for COVID-19 through PCR testing ( = 125), and those who received the Pfizer ( = 133), Sinopharm ( = 112), AstraZeneca ( = 20), or Sputnik ( = 2) vaccines.

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Objective: Spinal muscular atrophy (SMA) is common among various populations because the genetic makeup is monogamous due to consanguineous marriages. Two genes, i.e.

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Background: The association between weather conditions and the spread of COVID-19 was demonstrated by previous studies but focused on specific countries or investigated shorter periods of duration limiting the interpretation of the results.

Aim: To make an international comprehensive insight into the association between the weather conditions and the spread of COVID-19 by spanning many regions in the Northern and Southern hemispheres over a period of two years for the COVID-19 Outbreak.

Methods: The data were analyzed by using statistical description, linear and multiple regressions, and the Spearman rank correlation test.

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This study examines tourist satisfaction and its relationship with demographic variables in Nablus, Palestine. Two hundred two tourists were surveyed using a structured questionnaire to collect data on their satisfaction level and demographic information. The results reveal that the overall tourist satisfaction level in Nablus is high.

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Among various routes of metallic nanoparticle (NPs) fabrication, phytosynthesis has significant advantages over other conventional approaches. Plant-mediated synthesis of NPs is a fast, one-step, ecobenign, and inexpensive method with high scalability. Herein, silver (Ag) and gold (Au)-NPs were extracellularly synthesized using aqueous (H@Ag-, H@Au-NPs) leaf extracts.

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