Publications by authors named "Aljohara Alsaud"
Hepatic cancer is widely regarded as the leading cause of cancer-related mortality worldwide. Despite recent advances in treatment options, the prognosis of liver cancer remains poor. Therefore, there is an urgent need to develop more representative in vitro models of liver cancer for pathophysiology and drug screening studies.
View Article and Find Full Text PDFIntroduction: The purpose of this study was to assess the antifungal activity of silver nanoparticles (AgNPs) in combination with calcium hydroxide (Ca(OH)) against ().
Methods: AgNPs was mixed with pure Ca(OH) powder in an aqueous base. A standard suspension (1 × 10 bacterial cells/mL) of was prepared in a 96-well plate and incubated on shaker at 37 °C in 100% humidity to allow fungal biofilm formation in infected dentin slices ( = 98).
Article Synopsis
- Type 2 diabetes mellitus (T2DM) is becoming a major global health issue, with rising prevalence and significant health complications.
- The review investigates how epigenetic modifications, like DNA methylation and histone acetylation, play a role in the development and worsening of T2DM, affecting key processes such as obesity and insulin resistance.
- It emphasizes the importance of lifestyle factors, like diet and exercise, on epigenetics and discusses how targeting these modifications may lead to new treatments and preventative strategies for managing T2DM.
Article Synopsis
- This study compared the effectiveness of traditional instruction versus blended learning on dental students' performance in a preclinical endodontic course.
- Two groups of students were evaluated: those taught traditionally before the pandemic and those taught with a blended approach during the pandemic.
- The results showed that blended learning led to significantly higher written exam scores and overall preference among students, while practical competency scores were similar across both groups.
Background: Drug-resistant gram-negative bacteria (GNB) are a global public health threat, especially in intensive care units (ICU). This study explored the prevalence of drug-resistant Enterobacteriaceae infections in an ICU in Saudi Arabia. The appropriateness of the antibiotic therapies used and their ability to improve the clinical outcomes were also assessed.
View Article and Find Full Text PDFObjective: The aim of the study is to assess trends in public perceptions of health systems in 27 European Union (EU) member states following the financial crisis (2009-2013), in order to discuss observed changes in the context of the financial crisis.
Design: Repeated cross-sectional studies.
Setting: 27 EU countries.