Publications by authors named "Aliyye Karasu"
Article Synopsis
- Influenza leads to significant health issues, particularly in the elderly, many of whom fail to develop adequate antibody protection despite vaccination.
- A study examined high-risk individuals with different Human Leukocyte Antigen (HLA) class II types to see how these alleles influence immune response to the vaccine.
- Results indicated that those with specific HLA-DRB1*04∶01 and HLA-DPB1*04∶01 alleles had better antibody responses, suggesting that these genetic factors play a role in vaccine effectiveness.
Even when kidney allografts are well matched for human leukocyte antigen (HLA) and anti-HLA antibodies are not detected, graft rejection can still occur. There is evidence that some patients who lose their graft have antibodies specific for major histocompatibility complex (MHC) class I-related chain A (MICA) antigens. We investigated whether mismatching MICA alleles associates with MICA antibody production and graft rejection or dysfunction.
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