The dynamics of bla resistance genes in Salmonella Typhi.

Salmonella Typhi (S. Typhi) is an important pathogen causing typhoid fever worldwide. The emergence of antibiotic resistance, including that of bla genes encoding to TEM [Formula: see text]-lactamases has been observed.

Flankophile: a bioinformatic pipeline for prokaryotic genomic synteny analysis.

The Flankophile pipeline enables the analysis and visualization of flanking regions of prokaryotic sequences of interest on large data sets in one step and in a consistent manner. A specific tool for flanking region analysis with automated visualization has not been developed before, and Flankophile will make flanking region analysis easier and accessible to more people. Flankophile will be especially useful in the field of genomic epidemiology of acquired antimicrobial resistance genes.