Publications by authors named "Alix R McBrearty"
Objective: To investigate changes in owner-reported pain, interference of pain on function, and quality of life (QOL) in dogs with clinically suspected osteoarthritis when wearing a collar containing a static magnet.
Animals: 16 dogs over 5 years old weighing between 10 and 40 kg with a clinical diagnosis of osteoarthritis and on stable treatment.
Methods: A prospective, blinded crossover study in which dogs wore a collar containing a static magnet or placebo for two 4-week study arms separated by a 2-week washout period.
Background: Angiotensin-converting enzyme inhibitors (ACEi) are a recommended treatment for glomerular proteinuria. Frequency of response to ACEi and the association of achieving proposed urine protein-to-creatinine ratio (UPC) targets on survival is unknown.
Objectives: To determine response rates to ACEi therapy and whether a positive response is associated with improved survival.
Background: Folate deficiency in people can occur in conditions causing increased demand, including haemolytic anaemia. This has not been investigated in dogs with non-associative immune-mediated haemolytic anaemia (IMHA).
Methods: Cohort study of 15 dogs with non-associative IMHA.
Background: A previous study showed an association between owner-reported exposure to environmental tobacco smoke (ETS) and lymphoma in cats. This study aimed to investigate the association between ETS exposure and gastrointestinal lymphoma in cats, using hair nicotine concentration (HNC) as a biomarker.
Methods: This was a prospective, multi-centre, case-control study.
Comparison of axillary, tympanic membrane and rectal temperature measurement in cats.
J Feline Med Surg
December 2015
Objectives: Rectal temperature (RT) is routinely used to assess body temperature in cats but has limitations and can be poorly tolerated. Axillary temperature (AT) and tympanic membrane temperature (TMT) are reported alternatives. This study aimed to determine the differences between RT and AT, and between RT and TMT in cats.
View Article and Find Full Text PDFCats may demonstrate deafness due to a variety of aetiologies and the current preferred method for assessing auditory function is the brainstem auditory evoked response (BAER). The BAER has largely been replaced by otoacoustic emission (OAE) testing in human neonatal deafness screening as the equipment is more readily available, is cheaper and the test is less invasive and simpler. This is the first study to demonstrate that transient evoked OAEs (TEOAE) and distortion product OAEs (DPOAE) can be recorded in cats using commercially available equipment.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to examine how six clinical factors impact the outcomes of dogs diagnosed with generalized megaesophagus, pooling data from 71 client-owned dogs with confirmed esophageal dilation.
- The key findings showed that the median survival time was 90 days, with 26.7% of dogs dying before discharge; notably, aspiration pneumonia was linked to increased mortality, while later onset of symptoms (over 13 months) correlated with shorter survival.
- Ultimately, the study highlighted that aspiration pneumonia and the age of onset were significant predictors of survival, which vets should consider when discussing prognosis for affected dogs.
Background: Serum electrophoretic profiles in cats are poorly characterized with respect to the proteins that comprise the globulin fractions, and interpretation of the electrophoretograms is routinely done in the absence of information about identity of the proteins found within each fraction.
Objectives: The aims of this study were to compare protein fractions separated by serum protein electrophoresis (SPE) in healthy cats and in cats with lymphoma and to confirm some component proteins in the major fractions following SPE using tandem mass fingerprinting analysis (TMFA).
Methods: Total protein concentration was measured and agarose gel SPE performed on serum from 14 healthy cats and 14 cats with lymphoma.