Effect of the aspect ratio and wall heterogeneities on the mechanical behaviour of the aneurysm wall: Experimental investigation on phantom arteries.

The management of unruptured intracranial aneurysms (UIA) involves assessing the risk of rupture, which requires a thorough understanding of risk factors such as the geometric characteristics of the neck (neck size) or local structural heterogeneities. This study explores the impact of neck size on the rupture risk of the aneurysmal sac and examines how local heterogeneities, such as calcifications or variations in tissue composition, influence the mechanical response of the wall of a saccular aneurysm during the insertion of an innovative arterial wall deformation device (DDP). The results reveal that high aspect ratios (AR) are associated with increased hemodynamic stress, thereby raising the risk of rupture.