Age-Related Vitamin D Deficiency Is Associated with Reduced Macular Ganglion Cell Complex: A Cross-Sectional High-Definition Optical Coherence Tomography Study.

Background: Vitamin D deficiency is associated with smaller volume of optic chiasm in older adults, indicating a possible loss of the visual axons and their cellular bodies. Our objective was to determine whether vitamin D deficiency in older adults is associated with reduced thickness of the ganglion cell complex (GCC) and of the retinal nerve fibre layer (RNFL), as measured with high-definition optical coherence tomography (HD-OCT).

Methods: Eighty-five French older community-dwellers without open-angle glaucoma and patent age-related macular degeneration (mean, 71.

Vitamin D and macular thickness in the elderly: an optical coherence tomography study.

Purpose: Vitamin D insufficiency is associated with age-related macular degeneration. Our objective was to determine whether low serum 25-hydroxyvitamin D (25OHD) concentration was associated with macular thickness among older adults with no signs of macular dysfunction.

Methods: Sixty-two French older community-dwellers with no patent macular dysfunction (mean ± SD, 71.