Publications by authors named "Alistair K Templeton"

Three-dimensional measurement arrays are an efficient means of acquiring a distribution of data for patient plan delivery QA. However, the tie between plan integrity and traditional gamma-based analysis of these data are not clear. This study explores the sensitivity of such analysis by creating errors in Helical Tomotherapy delivery and measuring the passing rates with an ArcCHECK cylindrical diode array.

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Purpose: To validate an in-house optimization program that uses adaptive simulated annealing (ASA) and gradient descent (GD) algorithms and investigate features of physical dose and generalized equivalent uniform dose (gEUD)-based objective functions in high-dose-rate (HDR) brachytherapy for cervical cancer.

Methods: Eight Syed/Neblett template-based cervical cancer HDR interstitial brachytherapy cases were used for this study. Brachytherapy treatment plans were first generated using inverse planning simulated annealing (IPSA).

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Synopsis of recent research by authors named "Alistair K Templeton"

  • - Alistair K Templeton's research primarily focuses on advancements in radiation therapy, particularly in the realms of quality assurance and optimization methods for brachytherapy in cancer treatment
  • - His 2015 study demonstrated the efficacy of ArcCHECK-based gamma analysis in assessing the reliability of Helical Tomotherapy delivery, emphasizing the need for clarity in the relationship between plan integrity and analysis outcomes
  • - In his 2014 work on high-dose-rate brachytherapy for cervical cancer, Templeton validated an optimization program utilizing adaptive simulated annealing and gradient descent, showcasing the improved planning capabilities for better treatment outcomes