Microanatomy of the anterior uveoscleral outflow pathway in normal and primary open-angle glaucomatous dogs.

Objective: To compare the morphology of the uveoscleral (US) outflow pathway in normal and glaucomatous canines.

Animals Studied: 10 normal beagles, 10 beagles with inherited primary open-angle glaucoma, 4 cocker spaniels with spontaneous glaucoma.

Procedures: Formalin-preserved globes were sectioned tangentially and sagittally and treated with H&E, Masson's trichrome, or elastin stains or analyzed by immunohistochemistry to visualize smooth muscle actin.