Are we underestimating diabetes-related lower-extremity amputation rates? Results and benefits of the first prospective study.

Objective: The objective of this study was to accurately determine the incidence of lower-extremity amputation using prospective data collection and to compare the results with those obtained by retrospective methods.

Research Design And Methods: The study was carried out over a 3-year period in a large district general hospital covering a clearly defined and relatively static population. All diabetic inpatients with foot problems were identified and followed-up until discharge or death.