Publications by authors named "Alison M Riehm"
Article Synopsis
- There are currently no effective treatments for cognitive impairment in multiple sclerosis (MS), but research in a mouse model (EAE) shows promise for a specific neuropeptidase inhibitor called 2-PMPA.
- In this study, 2-PMPA was administered at various doses to determine its effectiveness in preventing cognitive decline without affecting physical symptoms, with 100 mg/kg proving most successful.
- Further tests showed that starting treatment with 100 mg/kg of 2-PMPA after symptoms appeared led to significant improvements in cognitive performance, suggesting potential for this treatment in MS-related cognitive issues.
