Displacement: Critical insights from flood-affected children.

Little is known about how children and young people are affected by evacuation following flooding. Participatory research using creative methods allowed us to elicit flood stories and recovery pathways over time. We found that children's relationships with space and place were severely challenged following evacuation from home.

Impact of a facial-ageing intervention versus a health literature intervention on women's sun protection attitudes and behavioural intentions.

This study was designed to investigate the impact of a facial-ageing intervention on women's sun protection attitudes and behavioural intentions, compared to a health literature intervention where participants viewed literature on the effect of ultraviolet (UV) exposure on health. Seventy women (35 in each condition) completed questionnaires at baseline and immediately post-intervention. The average age of the participants was 23.

Men's experiences of an appearance-focussed facial-ageing sun protection intervention: a qualitative study.

The study investigated men's experiences of taking part in an age-appearance-focussed intervention which involved seeing how their faces would age with and without UV exposure. Thirty-five men gave accounts of their experiences whilst taking part in the intervention, and eight men discussed their experiences retrospectively in focus groups. Transcripts were analysed using inductive thematic analysis.

Appearance-based interventions to reduce ultraviolet exposure and/or increase sun protection intentions and behaviours: a systematic review and meta-analyses.

Objectives: A systematic review and meta-analyses were conducted to identify and review research examining the impact of appearance-based interventions on sun protection intentions and/or ultraviolet (UV) exposure behaviour.

Methods: A search of 16 databases including PsycARTICLES, Cochrane Library and Web of Knowledge was conducted to identify studies examining the impact of appearance-based interventions on reducing UV exposure and/or increasing sun protection intentions and behaviours. A total of 21 articles met the inclusion criteria, and these studies were subjected to a systematic review and meta-analyses to determine the effectiveness of the interventions.

A qualitative study examining women's experiences of an appearance-focussed facial-ageing sun protection intervention.

The study was designed to investigate women's experiences of an appearance-focussed, facial-ageing, morphing intervention to show the effect of UV exposure on their skin. Forty-seven women aged 18-34 took part in the intervention: 35 women in individual sessions, and 12 in four focus groups. Transcripts were analysed using inductive thematic analysis.

Time dependence of protective post-exposure prophylaxis with human monoclonal antibodies against pathogenic SHIV challenge in newborn macaques.

In a primate model of postnatal virus transmission, we have previously shown that 1 h post-exposure prophylaxis (PEP) with a triple combination of neutralizing monoclonal antibodies (nmAbs) conferred sterilizing protection to neonatal macaques against oral challenge with pathogenic simian-human immunodeficiency virus (SHIV). Here, we show that nmAbs can also partially protect SHIV-exposed newborn macaques against infection or disease, when given as 12 or 24 h PEP, respectively. This work delineates the potential and the limits of passive immunoprophylaxis with nmAbs.

Live attenuated, nef-deleted SIV is pathogenic in most adult macaques after prolonged observation.

Objective: A live attenuated SIV vaccine strain, termed SIVmac239Delta3 and containing large deletions in, and the negative regulatory element, was previously shown to cause AIDS mostly in monkeys vaccinated as infants. In the present study, we demonstrate that SIVmac239Delta3 is pathogenic in most vaccinated adult monkeys, given enough time.

Methods: Eleven rhesus macaques vaccinated as adults with SIVmac239Delta3 were followed for extended periods (up to 6.

Quantitation of simian cytokine and beta-chemokine mRNAs, using real-time reverse transcriptase-polymerase chain reaction: variations in expression during chronic primate lentivirus infection.

Cytokines and beta-chemokines are important mediators of the immune system and are expressed in many infectious diseases. To study cytokine and beta-chemokine profiles during pathogenesis of lentiviral infection and progression to AIDS in rhesus macaques, we established new quantitative real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assays based on TaqMan chemistry. Using synthetic RNA standards, we quantified mRNAs of IL-2, IL-4, IL-6, IL-10, IL-12 p40, interferon gamma (IFN-gamma), tumor necrosis factor alpha (TNF-alpha), RANTES, macrophage inflammatory protein 1 alpha (MIP-1 alpha), and MIP-1 beta in unstimulated peripheral blood mononuclear cells (PBMCs) and lymph nodes from macaques chronically infected with SIV or SHIV.