Publications by authors named "Alison J Howell"
Article Synopsis
- The study examines the outcomes of left atrioventricular valve (LAVV) operations in patients with atrioventricular septal defects (AVSD) over a 20-year period, highlighting the challenges and complications involved.
- Out of 843 patients with repaired AVSDs, 59 (7.3%) underwent LAVV operations, with notable rates of reoperation and valve replacement among them, particularly in those who had complex repairs.
- Key risk factors for adverse events included having a lower body weight and needing early LAVV surgery, while cleft closure during initial surgery appeared to provide some protective benefits.
Impact of Genotype-Phenotype Interactions on Cardiovascular Function in Paediatric Loeys-Dietz Syndrome.
CJC Pediatr Congenit Heart Dis
April 2024
Background: The relationship between genotype and phenotypical vascular and cardiac properties in paediatric Loeys-Dietz syndrome (LDS) patients are not well characterized. This study explores the phenotypical differences in aortic properties and cardiac structural and functional parameters between paediatric LDS patients with and mutations.
Methods: We included 32 LDS patients with either (n = 17) or (n = 15) mutations.
Background: Cardiac rhabdomyoma are the most common cardiac tumour in childhood and are associated with tuberous sclerosis complex (TSC) up to 96% of infant cases. They classically manifest in the foetal and neonatal period, undergo spontaneous regression in the first years of life and are associated with arrhythmia in part due to interruption of normal conduction pathways by the tumour.
Case Summary: We present a case of a 3-year-old boy with a long-standing history of atrial ectopy who was incidentally found to be in atrial flutter due to a new, rapidly growing cardiac rhabdomyoma impacting ventricular function.
Aim: Staphylococcus aureus is an important cause of serious illness in children. Antibiotic resistance is an international problem and affects initial antibiotic choice. We aimed to describe susceptibility patterns of S.
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