An Incidental Finding of Whipple's Disease Masquerading as Nonspecific, Long-Standing Symptoms.

Whipple's disease is a rare bacterial infection that is often present for years prior to diagnosis. Symptoms are nonspecific in the early stages of presentation and are primarily gastrointestinal in nature. The disease may progress with more systemic symptoms including arthralgia, fever, lymphadenopathy, cardiovascular disease, and central nervous system involvement.

Evaluation of Sequential Oral Versus Intravenous Antibiotic Treatment of Bloodstream Infections.

Background: Intravenous (IV) antibiotics have historically been considered standard of care for treatment of bloodstream infections (BSIs). Recent literature has shown sequential oral (PO) therapy to be noninferior to IV antibiotics for certain pathogens and disease states. However, a gap exists in the literature for BSI caused by .

Erratum: Implementation of an asymptomatic bacteriuria assessment protocol for patients discharged from the emergency department - CORRIGENDUM.

[This corrects the article DOI: 10.1017/ash.2023.

Impact of restrictive urinalysis reflex to culture criteria at a large community hospital.

Treatment of asymptomatic bacteriuria (ASB) is a common, but often unnecessary, practice. Our objective was to determine the impact of restrictive urinalysis reflex to culture (UARC) criteria on rate of urine cultures (UC) ordered and ASB treatment. Criteria were modified from positive leukocyte esterase, positive nitrites, or white blood cells (WBC) >10 cells to only WBC >10 cells.

Impact of Gram-Negative Rod Bacteremia Rapid Diagnostic Testing and Real-Time Clinical Pharmacist Intervention.

The optimal method for implementing rapid diagnostic testing (RDT) into clinical practice has not been determined for gram-negative rod (GNR) bacteremia. At our institution, RDT was implemented in conjunction with real-time notification of results to decentralized clinical pharmacists. To determine the impact of RDT result notification plus real-time clinical pharmacist review on the management of GNR bacteremia.

Implementation of an asymptomatic bacteriuria assessment protocol for patients discharged from the emergency department.

Objective: We evaluated the impact of an asymptomatic bacteriuria (ASB) assessment protocol on the number of antibiotics prescribed for ASB after discharge from the emergency department (ED).

Design: Single-center, before-and-after, retrospective cohort study.

Setting: The study was conducted at a large community health system in North Carolina.