Retrobulbar pigmented peripheral nerve sheath tumor in a dog.

A 1-year-old male castrated Pug was referred for unilateral exophthalmos unresponsive to oral antibiotic and anti-inflammatory therapy. Clinical findings included exophthalmos of the left eye with lateral strabismus, resistance to retropulsion, and an elevated nictitans. Hematologic and biochemical analyses were within normal limits.

Impact of fungal species cultured on outcome in horses with fungal keratitis.

Purpose: To determine the significance of Aspergillus and Fusarium spp., as identified by culture, on clinical outcome in equine keratomycosis.

Methods: Retrospective analysis of 66 horses (66 eyes) evaluated at the NCSU-VH diagnosed with keratomycosis from which Aspergillus or Fusarium spp.

Equine eosinophilic keratitis in horses: 28 cases (2003-2013).

This retrospective case series evaluates husbandry and environmental conditions in relation to eosinophilic keratitis in horses. While no associations were found between disease and husbandry practices or specific environmental factors such as humidity or temperature, an increased prevalence of presentation in summer months was identified in this population of horses.

Presumed primary ocular lymphangiosarcoma with metastasis in a miniature horse.

A 7-year-old, 153.0-kg American Miniature mare presented for evaluation of keratoconjunctivitis of the right eye (OD). A superior palpebral conjunctival mass and stromal keratitis were diagnosed.

Histopathological features of equine superficial, nonhealing, corneal ulcers.

Objective: To evaluate corneal changes associated with chronic, nonhealing, superficial, corneal ulcers in horses via common histopathological stains.

Design: Retrospective study.

Animals: Twenty-four horses diagnosed with chronic, nonhealing, superficial, corneal ulceration.

Treatment of immune-mediated keratitis in horses with episcleral silicone matrix cyclosporine delivery devices.

Purpose: To describe the use of episcleral silicone matrix cyclosporine (ESMC) drug delivery devices in horses with immune-mediated keratitis (IMMK) with evaluation of tolerability and efficacy in long-term control of inflammation.

Methods: Retrospective study. ESMC implants (1.

Evaluation of the effects of tricaine methanesulfonate on retinal structure and function in koi carp (Cyprinus carpio).

Objective: To determine whether repeated exposure to clinically relevant concentrations of tricaine methanesulfonate (MS-222) would alter retinal function or induce histologically detectable retinal lesions in koi carp (Cyprinus carpio).

Design: Prospective, controlled, experimental study.

Animals: 18 healthy koi carp.

Immunohistochemical and immunopathologic characterization of superficial stromal immune-mediated keratitis in horses.

Objective: To describe the immunopathologic characteristics of superficial stromal immune-mediated keratitis (IMMK) immunopathologically by characterizing cellular infiltrate in affected corneas of horses.

Animals: 10 client-owned horses with IMMK.

Procedures: Immunohistochemical staining was performed on keratectomy samples with equine antibodies against the T-cell marker CD3 and B-cell marker CD79a (10 eyes) and the T-helper cytotoxic marker CD4 and T-cell cytotoxic marker CD8 (6 eyes).

Phacoemulsification and +14 diopter intraocular lens placement in a Saddlebred foal.

A 2-month-old, 110-kg Saddlebred filly presented for evaluation of bilateral cataracts. A hypermature cataract in the left eye (OS) and an incipient nuclear cataract in the right eye (OD) were diagnosed. Electroretinography and ocular ultrasound revealed no contraindications for surgical removal of the cataractous lens OS.

A retrospective comparison of surgical removal and subsequent CO2 laser ablation versus topical administration of mitomycin C as therapy for equine corneolimbal squamous cell carcinoma.

Objective:   To compare the complications and nonrecurrence rate following topical mitomycin C (MMC) therapy vs. CO(2) laser ablation for treating equine corneolimbal squamous cell carcinoma (SCC).

Study Design:   Retrospective study.

Diagnosis of intraocular lymphosarcoma in a dog by use of a polymerase chain reaction assay for antigen receptor rearrangement.

Case Description: A 12-year-old castrated male mixed-breed dog was evaluated because of blepharospasm and blindness affecting both eyes.

Clinical Findings: During examination and diagnostic testing of the dog, fine-needle aspirates of splenic nodules were examined microscopically and stage Vb multicentric large-cell lymphosarcoma was identified. Aqueocentesis was performed, and sample analysis revealed intraocular lymphosarcoma; B-cell neoplasia was confirmed by use of a PCR assay for antigen receptor rearrangement (PARR) performed on samples of aqueous humor.

Anomalous nasolacrimal openings in a 2-year-old Morgan filly.

This case report describes the clinical, diagnostic, computed tomography findings, and surgical treatment of a 2-year-old Morgan filly with bilateral, proximal, and distal anomalous nasolacrimal duct openings.

Aqueous humor and plasma concentrations of ciprofloxacin and moxifloxacin following topical ocular administration in ophthalmologically normal horses.

Objective: To determine the degree of ocular penetration and systemic absorption of commercially available topical ophthalmic solutions of 0.3% ciprofloxacin and 0.5% moxifloxacin following repeated topical ocular administration in ophthalmologically normal horses.

Effect of three treatment protocols on acute ocular hypertension after phacoemulsification and aspiration of cataracts in dogs.

Objective: To compare the effect of topical latanoprost, intracameral carbachol, or no adjunctive medical therapy on the development of acute postoperative hypertension (POH) and inflammation after routine phacoemulsification and aspiration (PA) of cataracts in dogs.

Design: Retrospective study.

Procedures: Dogs received either one drop of topical 0.

Infrared digital imaging of the equine anterior segment.

Ocular photographs are an increasingly important method of documenting lesions for inclusion in medical records, teaching purposes, and research. Availability of affordable high-quality digital imaging equipment has allowed for enhanced capture of desired images because of immediate on-camera viewing and editing. Conversion of the standard digital camera sensor to one that is sensitive to infrared light (i.

Surgical correction of severe strabismus and enophthalmos secondary to zygomatic arch fracture in a dog.

A grossly displaced segmental zygomatic arch fracture with marked ventro-lateral deviation of the left globe was diagnosed in a 3-month-old male German Shepherd dog following a bite injury. The fracture was approached via a modified lateral orbitotomy and a fragment of the lacrimal bone removed. The rostral portion of the fracture was stabilized with a 5-hole 2.

Epibulbar melanoma in a foal.

A case of epibulbar melanoma in a 6-month-old, gelded, chestnut Hanoverian foal is reported. The location and clinical appearance upon initial presentation led to the tentative diagnosis of staphyloma or a congenital mass of unknown origin. An attempt was made to surgically excise the mass under general anesthesia, but due to its infiltrative nature and intraoperative appearance, most, but not all was removed without compromising the integrity of the globe.

Evaluation of concentration of voriconazole in aqueous humor after topical and oral administration in horses.

Objective: To determine penetration of topically and orally administered voriconazole into ocular tissues and evaluate concentrations of the drug in blood and signs of toxicosis after topical application in horses.

Animals: 11 healthy adult horses.

Procedure: Each eye in 6 horses was treated with a single concentration (0.