Evaluating the impact of testosterone replacement therapy on carotid atherosclerosis: a systematic review and meta-analysis.

This meta-analysis investigates the association between testosterone replacement therapy [TRT] and carotid artery atherosclerosis. 3 databases were searched for studies up to June 2023 per the PRISMA guidelines. The eligibility criteria comprised RCTs and observational studies involving hypogonadal males receiving exogenous testosterone, in which CIMT was assessed.