Publications by authors named "Alisha Sial"

Background: Degenerative Cervical Myelopathy (DCM) is the most common cause of non-traumatic, chronic spinal cord dysfunction worldwide, causing debilitating disability with a diminishing quality of life. The natural history of DCM is poorly understood. This is a preliminary report of the first 60 patients recruited to the MYelopathy NAtural History (MYNAH) Registry.

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Article Synopsis
  • Degenerative Cervical Myelopathy (DCM) is a serious condition resulting from spinal cord compression due to age or genetic factors, commonly seen in adults.
  • Symptoms of DCM vary widely, ranging from neck pain and stiffness to severe issues like paralysis, but neck pain alone isn't a reliable indicator of the disease.
  • The paper explores the connection between DCM and chronic neck pain while considering its causes and neurological impacts, emphasizing the importance of not overlooking neck pain during diagnosis.
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Orthopaedic spine surgery, particularly for adult spinal deformity, demands extensive expertise due to its complex pathologies. Surgical success hinges on precise planning, multidisciplinary collaboration, and advanced techniques to correct deformities and restore spinal alignment. This study investigates the efficacy of a Combined Monthly Scoliosis Clinic initiated in April 2022 at Spine Service, St George Private Hospital.

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Purpose: Increased intramedullary signal intensity (IISI) on T2 weighted MRI scan (T2WI) can be a radiological feature of spinal cord degeneration. However, the association of IISI to degeneration of the spinal column that protects the spinal cord remains unclear. The purpose of this study was to determine the prevalence of IISI and analyze the independent relationship between IISI and cervical degenerative parameters on X-ray and magnetic resonance imaging (MRI).

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Importance: Adolescent idiopathic scoliosis (AIS) is the most common pediatric spinal disorder. Routine physical examinations by trained personnel are critical to diagnose severity and monitor curve progression in AIS. In the presence of concerning malformation, radiographs are necessary for diagnosis or follow-up, guiding further management, such as bracing correction for moderate malformation and spine surgery for severe malformation.

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Objective: Whilst microdiscectomy is an excellent reliever of pain for recalcitrant lumbar disc herniation (LDH), it has a high failure rate over time due to the ensuing reduction in mechanical stabilization and support of the spine. One option is to clear the disc and replace it with a nonhygroscopic elastomer. Here, we present the evaluation of biomechanical and biological behavior of a novel elastomeric nucleus device (Kunovus disc device [KDD]), consisting of a silicone jacket and a two-part in situ curing silicone polymer filler.

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Background: The anterior approach to the cervical spine is the most commonly used surgery with effective decompression and less surgical trauma. Anterior plate construct (APC) is considered a standard technique. However, it appears to cause implant failure and postoperative dysphagia.

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Background: Cerebrospinal fluid (CSF) is thought to flow into the brain via perivascular spaces around arteries, where it mixes with interstitial fluid. The precise details concerning fluid outflow remain controversial. Although fluid dynamics have been studied in the brain, little is known about spinal cord fluid inflow and outflow.

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