Synopsis of recent research by authors named "Alisha F Khan"
- Alisha F Khan's recent research primarily focuses on the role of immunotherapy in treating gastroesophageal cancers, emphasizing the potential benefits of neoadjuvant and perioperative strategies over conventional adjuvant therapies for improving patient outcomes.
- One notable study highlights how the combination of the multi-gene tyrosine kinase inhibitor sitravatinib with PD-1 blockade leads to enhanced cytotoxic T-cell infiltration through M2 to M1 tumor macrophage reprogramming, providing insight into novel therapeutic combinations for esophageal adenocarcinoma.
- The author's work underscores the importance of addressing unmet needs in esophagogastric cancer treatment and exploring innovative approaches to leverage the immune system against tumor progression.