Publications by authors named "Alisa Shaimardanova"
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Synopsis of recent research by authors named "Alisa Shaimardanova"
- Alisa Shaimardanova's research primarily focuses on the development and application of gene and cell therapies for hereditary neurodegenerative diseases (hNDDs) and lysosomal storage disorders, emphasizing the potential therapeutic benefits of growth factors, enzyme enhancement, and genetically modified stem cells.
- Recent studies by Shaimardanova have examined innovative approaches such as using adeno-associated virus (AAV) vectors for gene therapy in conditions like metachromatic leukodystrophy and evaluating the efficacy of mesenchymal stem cells to increase the activity of β-hexosaminidase A, targeting diseases like GM2 gangliosidoses.
- Her work highlights the importance of personalized treatment strategies and safe delivery methods for gene therapy, aiming to address challenges in treating severe genetic disorders, and showcases preliminary findings that illustrate the promise of advanced therapeutic modalities in managing complex neurodegenerative conditions.
