Synopsis of recent research by authors named "Alisa Agne"
- Alisa Agne's research primarily focuses on the cytokine interleukin-1β (IL-1β) and its regulation in various inflammatory conditions, emphasizing the role of different receptors and proteins in modulating its release and maturation during immune responses and surgeries.
- Significant findings include the discovery that elevated preoperative C-reactive protein (CRP) may inhibit IL-1β release during lung cancer surgeries, and that amyloid beta peptide can reverse cholinergic control of IL-1β secretion in the context of Alzheimer's disease.
- Agne's studies explore novel interactions and mechanisms involving cholinergic receptors and proteins like SLPI and Alpha-1 Antitrypsin to control IL-1β, highlighting their potential therapeutic implications in preventing systemic inflammation and improving outcomes in surgical and pathological settings.
