Publications by authors named "Alireza Sheidary"
We investigated the delivery of sorafenib (SFB) to breast cancer spheroids by natural killer cell-derived exosomes (NK-Exos). SFB-NK-Exos were constructed by electroporation. Their antitumor effects were evaluated by methyl thiazolyl tetrazolium, acridine orange/ethidium bromide, 4',6-diamidino-2-phenylindole, annexin/propidium iodide, scratch and migration assay, colony formation, RT-PCR, western blot and lipophagy tests.
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- * Current antiviral treatments face challenges like drug resistance and lack of specificity, prompting the need for innovative nanotherapeutic and nano-vaccine approaches.
- * Utilizing nanoparticles in vaccine and antiviral agent development is promising, especially for targeting respiratory viruses like SARS-CoV-2, which can cause serious conditions like acute respiratory distress syndrome.
Carbon monoxide (CO) poisoning causes cardiotoxicity and so far, no definite antidote has been proposed to overcome CO-induced adverse outcomes. Hesperidin, a citrus flavonoid, has shown cardio-protective effects in cardiac ischemia/reperfusion models. This study investigated the protective effects of hesperidin against CO-induced cardiac injury.
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