Publications by authors named "Alireza Oraii"
Background: Patients undergoing first-time atrial fibrillation (AF) ablation can benefit from targeting non-pulmonary vein (PV) triggers. Preprocedural identification of high-risk individuals can guide planning of ablation strategy. This study aimed to create a preprocedural screening tool to identify patients at risk of non-PV triggers during first-time AF ablation.
View Article and Find Full Text PDFObjectives: Atrial fibrillation is the most common complication of cardiac surgery and occurs frequently in patients without a history of the arrhythmia. We conducted a systematic review and meta-analysis of randomized controlled trials to assess whether prophylactic ablation during cardiac surgery in patients without a history of atrial fibrillation prevents atrial fibrillation.
Methods: We searched CENTRAL, MEDLINE and Embase from inception to August 2024.
Background: The ability to predict recovery of left ventricular ejection fraction (LVEF) in response to guideline-directed therapy among patients with nonischemic cardiomyopathy is desired. We sought to determine whether left ventricular endocardial unipolar voltage measured during invasive electroanatomic mapping could be used to predict LVEF recovery among those with recent-onset nonischemic cardiomyopathy.
Methods: We analyzed the left ventricular voltage maps of patients included in the eMAP trial (Electrogram-Guided Myocardial Advanced Phenotyping; NCT03293381), a prospective, nonrandomized, interventional trial conducted at 2 institutions between 2017 and 2020.
Background: The importance of nonpulmonary vein (PV) triggers for the initiation/recurrence of atrial fibrillation (AF) is well established.
Objectives: This study sought to assess the incremental benefit of provocative maneuvers for identifying non-PV triggers.
Methods: We included consecutive patients undergoing first-time AF ablation between 2020 and 2022.
Article Synopsis
- The study examines the effectiveness of endocardial (ENDO) ablation in treating arrhythmogenic right ventricular cardiomyopathy (ARVC), specifically focusing on its long-term outcomes and factors influencing survival without ventricular tachycardia (VT).
- A total of 74 patients with ARVC underwent ENDO-only VT ablation between 1998 and 2020, with about 66% achieving noninducibility of VT and a median follow-up of 6.6 years revealing that over 54% remained free of VT recurrence.
- Important predictors for long-term VT-free survival included being over 45 years at diagnosis and achieving VT noninducibility, suggesting that ENDO-only ablation could be a viable initial
Article Synopsis
- Epicardial access is important during ventricular tachycardia ablation, and the study compares two methods: traditional ConvEpi access and a newer method called EpiCO, which involves puncturing coronary venous branches.
- The study included 153 patients and found that both methods had similar success rates, but ConvEpi was quicker and associated with more complications, especially significant bleeding.
- Overall, EpiCO access showed a decrease in major complications and bleeding compared to ConvEpi, suggesting it might be a safer option for patients.
Background: Opium consumption has been an overlooked health issue in the Iranian population, and the prognostic role of opium consumption in patients undergoing coronary revascularization is unknown.
Hypothesis: We aimed to assess the association between opium consumption and long-term cardiovascular outcomes after percutaneous coronary intervention (PCI).
Methods: We screened 2203 consecutive patients who underwent elective PCI between April 2009 and April 2010 at Tehran Heart Center.
Importance: Catheter ablation is associated with reduced heart failure (HF) hospitalization and death in select patients with atrial fibrillation (AF) and heart failure with reduced ejection fraction (HFrEF). However, the benefit in patients with HF with preserved ejection fraction (HFpEF) is uncertain.
Objective: To investigate whether catheter ablation for AF is associated with reduced HF-related outcomes according to HF phenotype.
Article Synopsis
- The study focuses on identifying factors that predict in-hospital and long-term mortality in patients with ST-elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI).
- Analyzing data from 1,123 patients, researchers found that older age, lower ejection fraction, lower mean arterial pressure, and higher white blood cell count were linked to higher in-hospital mortality rates, while older age and lower mean arterial pressure, along with higher blood urea, predicted long-term mortality.
- The findings highlight the need for enhanced care and monitoring of STEMI patients, particularly those at greater risk due to age and blood pressure levels.
Background: Targeting non-pulmonary vein triggers (NPVTs) after pulmonary vein isolation may reduce atrial fibrillation (AF) recurrence. Isoproterenol infusion and cardioversion of spontaneous or induced AF can provoke NPVTs but typically require vasopressor support and increased procedural time.
Objective: The purpose of this study was to identify risk factors for the presence of NPVTs and create a risk score to identify higher-risk subgroups.
Background And Aims: Mineralocorticoid receptor antagonists (MRAs) improve cardiovascular outcomes in a variety of settings. This study aimed to assess whether cardioprotective effects of MRAs are modified by heart failure (HF) and atrial fibrillation (AF) status and to study their impact on AF events.
Methods: MEDLINE, Embase, and Cochrane Central databases were searched to 24 March 2023 for randomized controlled trials evaluating the efficacy of MRAs as compared with placebo or usual care in reducing cardiovascular outcomes and AF events in patients with or at risk for cardiovascular diseases.
Background: The present study aimed to investigate the association between acute cardiac injury (ACI) and outcomes in hospitalized patients with coronavirus disease 2019 (COVID-19) in Iran.
Methods: The current cohort study enrolled all consecutive hospitalized patients with COVID-19 (≥ 18 y) who had serum high-sensitivity cardiac troponin-I (hs-cTnT) measurements on admission between March 2020 and March 2021. ACI was determined as hs-cTnT levels exceeding the 99th percentile of normal values.
Persistent AF Ablation: What Else to Do and Why After Pulmonary Vein Isolation?
JACC Clin Electrophysiol
November 2023
Article Synopsis
- A study analyzed ECG data from 7630 adults aged 35 and older to investigate age and gender differences in ECG parameters and abnormalities, finding notable variations between groups.
- Results showed that women had a higher average heart rate, while men exhibited longer QRS duration and RR intervals, with major ECG abnormalities slightly more prevalent in men, but differences weren't statistically significant.
- The study concluded that both major and minor ECG abnormalities were more common in men, and the likelihood of major ECG abnormalities increased significantly with age, particularly in participants over 65.
Introduction: This study aimed to investigate the clinical and angiographic characteristics of patients with ST-elevation myocardial infarction who experienced primary percutaneous coronary intervention failure.
Method: This retrospective observational study was derived from the Primary Angioplasty Registry of Sina Hospital (PARS). A total of 548 consecutive patients with ST-elevation myocardial infarction who underwent primary percutaneous coronary intervention between November 2016 and January 2019 were evaluated.
Article Synopsis
- Tobacco use is a significant health issue globally, particularly in low/middle-income countries, and a study was conducted in Tehran, Iran to evaluate the prevalence of different forms of tobacco use among 8,272 participants.
- The findings revealed that 19.8% were current tobacco users, with higher rates among younger individuals and men, and identified that education level, body mass index, physical activity, and use of opium and alcohol were associated with higher tobacco use.
- The study highlights the need for targeted interventions in Tehran to address the high prevalence of tobacco use, noting specific risk factors and the differing patterns of use between genders.
Article Synopsis
- The study aimed to assess the prevalence of type 2 diabetes and its management among adults in Tehran, revealing significant public health insights.
- Results showed a diabetes prevalence of 16.7% and impaired fasting glucose (IFG) at 25.1%, with higher rates observed in specific districts of the city.
- Key factors linked to higher diabetes odds included older age, male sex, obesity, and pre-existing health conditions, while awareness and treatment rates among diabetic individuals were relatively high, though effective glycemic control was lower at 31.7%.
Article Synopsis
- High blood pressure (BP) is often unnoticed and poorly managed, contributing significantly to health issues and deaths in the population.
- A study of over 8,000 adults in Tehran revealed a hypertension prevalence of 36.5%, with only 68.2% aware of their condition, 53.3% receiving treatment, and 40.4% having blood pressure under control.
- Findings indicated that women demonstrated better awareness, treatment, and control than men, and despite a higher prevalence in northern Tehran, that region also showed better treatment and control outcomes.