Publications by authors named "Alireza Malektojari"

Article Synopsis
  • The study investigates how diabetes and prediabetes relate to the risk of developing chronic kidney disease (CKD), considering factors like age, gender, lifestyle, and blood pressure.
  • The research involved 4,063 participants aged 35 to 70 in Iran, assessing CKD prevalence using specific diagnostic criteria, revealing a CKD prevalence of 15.3%, with higher rates in diabetic individuals (29.6%).
  • The findings highlight the need for early detection and management of CKD risk factors, especially for high-risk groups, to prevent CKD progression and improve health outcomes.
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Systemic lupus erythematosus (SLE) is a chronic autoimmune disease primarily impacting women of childbearing age. While pregnancy and hormonal stress can trigger SLE flare-ups, the effects of assisted reproductive therapies (ARTs) on SLE patients are not well defined. We conducted a search of PubMed/Medline, Embase, and CENTRAL until March 20, 2024, to find observational studies assessing the prevalence of SLE flares and pregnancy outcomes following ARTs.

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Article Synopsis
  • About 25% of total knee replacement patients experience ongoing pain, so identifying those at higher risk is crucial for better management.
  • A review of 30 studies involving over 26,000 patients found that factors like pain catastrophizing, younger age, and moderate-to-severe post-operative pain significantly increase the risk of persistent pain.
  • While some evidence suggested links to female sex and higher pre-operative pain, other factors like BMI and range of motion showed no significant associations.
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Objectives: We will evaluate the efficacy and safety of Ivermectin in patients with mild and moderately severe COVID-19.

Trial Design: This is a phase 3, single-center, randomized, open-label, controlled trial with a 2-arm parallel-group design (1:1 ratio).

Participants: The Severe Acute Respiratory Syndrome Departments of the Shahid Mohammadi Hospital, Bandar Abbas, Iran, will screen for patients age ≥ 20 years and weight ≥35 kg for the following criteria: Inclusion criteria for patients with mild COVID-19 symptoms (outpatients) 1.

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