Publications by authors named "Alireza M Manuchehri"
Article Synopsis
- The study investigates the impact of soy phytoestrogen supplementation on thyroid function in patients with subclinical hypothyroidism, amidst concerns about possible negative effects on thyroid health.
- Conducted as a randomized, double-blind, crossover trial with 60 participants, the study compared low-dose and high-dose phytoestrogen groups for 8 weeks each.
- Results indicated a significant increase in the risk of progressing to overt hypothyroidism with high-dose supplementation, along with beneficial effects on blood pressure, insulin resistance, and inflammation markers, though lipid profiles did not change.
Article Synopsis
- Dopamine agonists (DAs) can potentially reduce the size and secretion of prolactinomas by improving the tumor's blood vessel functionality, as visualized through DCE-MRI.
- A study with 23 participants (including patients with various types of prolactinomas and normal volunteers) showed that DAs significantly reduced prolactin levels and vascular parameters in most patients but not in normal subjects.
- The findings suggest that changes in tumor vascularity occur before any reduction in tumor size, and lack of these changes shortly after treatment may indicate resistance to DAs, possibly necessitating surgical intervention.
Background: B-type natriuretic peptides and N-terminal pro-B-type natriuretic peptides (NT-proBNP) have been suggested as being useful for the diagnosis of congestive heart failure. We have shown previously that changes in thyroid function are associated with changes in concentrations of other low molecular weight molecules. Therefore, the aim of this study was to assess whether similar changes occurred with NT-proBNP concentrations following treatment of thyroid dysfunction.
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