Publications by authors named "Alireza Ghadrdan"
Article Synopsis
- Enrofloxacin, a fluoroquinolone antibiotic, is investigated for its effects on growing lamb articular cartilage, due to its excessive use and potential skeletal impact.
- The study involved twelve male lambs, divided into control, therapeutic, and toxic groups, to examine changes in collagen content and gene expression related to cartilage health, specifically focusing on Sox9 and caspase-3.
- Findings indicated that enrofloxacin led to decreased matrix components and increased chondrocyte apoptosis, with more pronounced effects in the toxic group compared to the therapeutic group, raising concerns about its impact on cartilage development.
