Recent advances in bioactive materials: Future perspectives and opportunities in oral cancer biosensing.

Bioactive materials and biosensing technologies are emerging as pivotal tools in the early detection and management of oral cancer, a disease characterized by high morbidity and mortality rates. Recent advancements in nanotechnology have facilitated the development of innovative biosensors that utilize bioactive materials for non-invasive diagnostics, particularly through salivary analysis. These biosensors, including electrochemical, optical, and molecular types, target specific biomarkers such as DNA, RNA, and proteins associated with oral cancer.

ABCG2, SCN1A and CYP3A5 genes polymorphism and drug-resistant epilepsy in children: A case-control study.

Purpose: Drug Resistant -Epilepsy is still a major challenge in pharmacotherapy of epilepsy. Pharmacogenetic pathways are one of the most important elements that can help clinicians determine medication response and provide more efficient drug therapy, especially in cases of drug resistance. Genetic alterations in drug target and transporter proteins, in part, could explain the development of drug-resistant epilepsy.

Evaluation of the Effect of Platelet-Rich Fibrin on Wound Healing at Split-Thickness Skin Graft Donor Sites: A Randomized, Placebo-Controlled, Triple-Blind Study.

Split-thickness skin grafting (STSG) is widely used to heal wounds resulting from trauma, burns, and chronic wounds. This study aimed to determine the true effect of platelet-rich fibrin (PRF) on patients with burn wounds requiring STSG during treatment of donor wounds. This randomized, triple-blind clinical trial was conducted on patients who referred to the burn ward of Vasei Hospital of Sabzevar, Iran, from May 2017 to May 2018.

Adaptive neuro-fuzzy sliding mode control of multi-joint movement using intraspinal microstimulation.

During the last decade, intraspinal microstimulation (ISMS) has been proposed as a potential technique for restoring motor function in paralyzed limbs. A major challenge to restoration of a desired functional limb movement through the use of ISMS is the development of a robust control strategy for determining the stimulation patterns. Accurate and stable control of limbs by functional intraspinal microstimulation is a very difficult task because neuromusculoskeletal systems have significant nonlinearity, time variability, large latency and time constant, and muscle fatigue.

Potential of human umbilical cord matrix and rabbit bone marrow-derived mesenchymal stem cells in repair of surgically incised rabbit external anal sphincter.

Purpose: Anal sphincter defects and fecal incontinence are complicated surgical problems. We investigated the ability of human umbilical cord matrix (hUCM) and rabbit bone marrow (rBM) stem cells to improve anal sphincter incontinence due to induced sphincter defects without surgical repair.

Methods: We harvested hUCM cells from human Wharton's jelly and rBM stem cells from rabbit femurs and tibias.