Topical Olive Leaf Extract Improves Healing of Oral Mucositis in Golden Hamsters.

Statement Of The Problem: Oral mucositis (OM) is a common side effect of anti-cancer drugs and needs significant attention for its prevention.

Purpose: This study aimed to evaluate the healing effects of olive leaf extract on 5-fluorouracil-induced OM in golden hamster.

Materials And Method: OM was induced in 63 male golden hamsters by the combination of 5-fluorouracil injections (days 0, 5 and 10) and the abrasion of the cheek pouch (days 3 and 4).