Recent studies indicate that the FTO gene influences body weight by affecting the expression of the IRX3 gene, which is linked to obesity.
The review analyzed various articles from 2000 to 2019, focusing on factors like polymorphism, BMI, and the IRX3 gene across multiple scientific databases.
Findings suggest mixed results regarding IRX3's role in obesity, with some research showing that increased expression correlates with higher body weight while others indicate the opposite; more research is needed to clarify these relationships.