Publications by authors named "Alira Fraga-Olvera"
[Delayed hypersensitivity reactions to drugs: Group Report of the Drug Allergy Committee of the Mexican College of Clinical Immunology and Allergy (CMICA).].
Rev Alerg Mex
September 2024
Article Synopsis
- Adverse drug reactions (ADRs) can be classified into Type A (pharmacokinetics-related) and Type B (immune response-related), with Type B reactions being less well-defined and often categorized into immediate and delayed types.
- This review aims to explore the immunological mechanisms behind delayed hypersensitivity reactions to medications, highlighting their complexities.
- Findings discuss the classification, clinical signs, diagnosis, treatment plans, and overall prognosis of delayed hypersensitivity, emphasizing the need for prompt, tailored approaches by healthcare professionals.
Background: Any substance used as a treatment for any disease can produce harmful or unpleasant events called adverse drug reactions (ADRs). They are due to inherent biological effects of the drug and are caused by immunological and non-immunological mechanisms.
Objectives: To describe the immunological mechanisms of hypersensitivity reactions (HSR) to drugs, their epidemiology, risk factors, classification, clinical manifestations, diagnosis, treatment, and prognosis.
[Prevalence of persistent hypogammaglobulinemia in patients with autoimmune rheumatic disease who received treatment with Rituximab in a national medical center in Mexico].
Rev Alerg Mex
April 2023
Objective: To describe the prevalence of persistent hypogammaglobulinemia in patients receiving Rituximab as a treatment for autoimmune rheumatological diseases.
Methods: A transversal, retrospective and unicentric study, carried out in patients with autoimmune rheumatic diseases who were admitted to the Rheumatology service of the Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, Mexico City, to receive treatment with rituximab between January 2013 and January 2018.