[Role of induction chemo- and radiotherapy in the treatment of locally advance breast cancer].

336 patients with locally-advanced breast cancer underwent neoadjuvant chemotherapy or chemoradiotherapy. Increase in T- and N-indices (change of stage after neoadjuvant chemotherapy) proved an important prognostic factor. Survival rates correlated with clinical effect and dropped as it diminished.

[Endovascular papillary angioendothelioma].

One case of a rare vascular tumor which occurs mainly in the childhood is presented. The tumor has a tendency to recurrence and metastases into the regional lymph nodes in spite of a relatively mature structure.

[Atypical adenomatous hyperplasia of the lung].

Clinicomorphological analysis was performed in 12 cases of atypical adenomatous hyperplasia of the lung (AAH). This is the proliferative lesion consisting of atypical epithelial cells along the alveolar septa which are found incidentally during pathologic examination of the lung resected because of cancer. We studied morphological and biological characteristics of AAH cells including cytodifferentiation, proliferative activity, tumor-suppressor genes.

[Cystic epithelioma in the epidermal cyst].

A case of skin tumor-cystic epithelioma is reported. Differential-diagnostic features of its distinction from squamous-cell carcinoma are given.

[Carcinoid tumors of the lung].

Detailed cytological, histological and electron microscopic characteristics of pulmonary carcinoid tumors are listed on the basis of surgical clinic material. Various variants of the carcinoid tumors structure, their differential diagnosis are presented.

[Carcinoid of the kidney].

Rare location of carcinoid tumour in the kidney is reported. The diagnosis was established on the basis of histological and ultrastructural investigation.

[Osteochondroplastic tracheobronchopathy].

14 cases of osteochondroplastic tracheobronchopathy (OT) are studied histologically. The disease is characterized by formation of cartilage and bone tissue in the submucosa of the trachea and bronchi outside their own cartilagenous carcass. Its histogenesis is not clear and is attributed to chronic bronchitis, specific inflammation, dysembryogenetic alterations, endocrine disorders, environmental and occupational hazards, amyloidosis of the trachea.

[The degree of tumor vascularization as a prognostic factor of the efficacy of neoadjuvant polychemotherapy in breast cancer].

A procedure for obtaining microcirculation coefficient is described. It is based on the phenomenon of formation of a focus of radionuclide hyperfixation on scintigrams of tumor area due to embolization of its arterioles and precapillaries with radionuclide. The method was used in 26 breast cancer patients before neoadjuvant chemotherapy.

[The fibroepithelial variant of basal-cell skin cancer (Pincus' "premalignant" fibroepithelioma)].

12 cases of the basal cell carcinoma fibroepithelial variant are studied morphologically. This variant of basal cell carcinoma is erroneously diagnosed as adenoid variant of seborrheic keratosis, tubular syringoadenoma or the reverse. Main differential-diagnostic criteria allowing to distinguish a fibroepithelial variant of basal cell carcinoma from an adenoid variant of seborrheic keratosis are multicentric foci of superficial basalioma as well as the absence of hyperkeratosis and intraepithelial carcinomatous cysts.

[Epidermoid thymoma--a variety of thymus gland cancer].

Epidermoid thymoma was referred to thymal malignancies after an evaluation of the data on its clinical course and microscopic structure. This tumor may be diagnosed preoperatively on the basis of an analysis of clinico-roentgeno-endoscopic data and findings of a cytological, histological and electron-microscopic examinations.

[Pathological anatomy of thymus gland tumors].

The paper presents detailed morphological characteristics of 31 thymomas and 25 microscopically similar neoplasias of the anterior mediastinum (carcinoid, seminoma, lymphogranulomatosis, angiofollicular lymphoma, etc). The term "thymoma" is determined as a tumour consisting of two components: mandatory epithelial one and lymphocytes. The diversity of the morphological picture of thymomas is determined mainly by the variability of the epithelial component.

[Intracranial cylindroma (cylindromatous epithelioma)].

A case with intracranial cylindroma is reported. Intracranial cylindroma possesses local destructive growth and may recur repeatedly and produce metastases; it is localized on the base of the skull in the chiasmal area or, more frequently, in the region of the trigeminal ganglion. Cylindroma of chiasmal localization develops from ectopic mucous glands of the nose or nasal sinuses, whereas cylindroma of the trigeminal ganglion arises from the glandular epithelium of the auditory tube.

[Lymphogranulomatosis of the thymus gland ("granulomatous thymoma")].

Thirteen tumors of questionable genesis located in the thymus were studied. The microscopical structure of these tumors was identical to lymphogranulomatosis of other localization. Reactive proliferation of the thymic epithelium and cyst formation are characteristic of lymphogranulomatosis primarily developing in the thymus.