Publications by authors named "Alioune Diallo"
Article Synopsis
- Sickle cell emergencies are a leading reason for hospitalizations in patients with sickle cell disease, causing significant financial strain and increased health risks.
- A study tracked 112 adults with sickle cell emergencies over four months, revealing a 38.41% readmission rate within 30 days, predominantly due to vaso-occlusive crises and acute chest syndrome.
- Key factors predicting readmission included having a job, low levels of fetal hemoglobin, and certain blood cell counts (neutrophilia, lymphocytosis, thrombocytosis).
Article Synopsis
- The study focused on managing acute pain in adults with sickle cell disease (SCD), particularly during vaso-occlusive crises (VOC), which occur when sickle cells block microvessels, leading to severe pain.* -
- An analysis of 118 cases revealed that most patients (86.61%) had the SS sickle cell phenotype, with predominant pain in the lower limbs and spine, and a majority experiencing intense to unbearable pain.* -
- The findings underscore the effectiveness of multimodal analgesia as a treatment approach, while also indicating significant variability in pain management practices, suggesting a need for tailored recommendations.*
is a cosmopolitan saprophytic fungus that infests several foodstuffs and is associated with adverse effects in humans. In Senegal, significant losses of groundnut production are mainly due to contamination caused by this species. This study evaluated in vitro antifungal activities of , and essential oils against isolated from peanut seeds.
View Article and Find Full Text PDFThe Hodgkin variant Richter syndrome (HvRS) is an infrequent complication occurring in 1% of lymphocytic lymphoma/chronic lymphocytic leukemia patients. We report a case of HvRS diagnosed in Sub-Saharan Africa. A 63-year-old patient was consulted for the investigation of an abdominal mass that had been evolving for 5 years prior to admission.
View Article and Find Full Text PDFSUMMARYCOVID-19 infection has emerged as a comorbidity that can significantly increase morbidity and mortality in sickle cell patients with ACS (acute thoracic/chest syndrome). The aim of our study was to assess COVID-19-related morbidity and mortality in sickle cell patients with ACS. This was a retrospective, descriptive study of patient records followed over a 36-month period from January 2020 to December 2022.
View Article and Find Full Text PDFRosai-Dorfman disease (RDD) is a benign histiocytic proliferation that results in nodal and extranodal involvements. It is a rare disease, with fewer than 1,000 cases reported in the literature, which explains its lack of knowledge by physicians and the lack of codified therapeutic strategies. We report the case of an 8-year-old girl who presented a rapidly progressive cervical lymph node mass; the diagnosis of RDD was made based on histology and immunohistochemistry.
View Article and Find Full Text PDFCombretum micranthum (Combretaceae) is a medicinal plant widely known and used in Africa to treat a variety of conditions such as diabetes, fever, coughs, bronchitis, diarrhea, pain, malaria and liver disorders, among others. Due to its wide traditional use, in this review, published scientific reports on its composition and pharmacological properties were explored by conducting a literature search of databases. To date, 155 organic compounds including 34 flavonoids, 16 phenolic acids, 14 alkaloids, 15 fatty acids, 14 terpenoids/steroids, 24 amino acids, 8 carbohydrate substances and 30 other organic compounds have been identified from this plant.
View Article and Find Full Text PDFContext And Objectives: Blood transfusions (BT) remain a mainstay of therapy for patients with sickle cell disease (SCD) but pose significant clinical challenges. We aim to assess infectious markers, red cell alloimmunization, and iron overload secondary to BT in SCD patients.
Materials And Methods: This case-control study included 253 SCD (153 SCD-transfused and 100 SCD non-transfused).
Objective: To compare, at the community level, the cost-effectiveness of oxytocin and misoprostol for the prevention of postpartum hemorrhage (PPH).
Methods: The present cost-effectiveness study used data collected during a randomized trial that compared the prophylactic effectiveness of misoprostol and oxytocin for the prevention of PPH in a rural setting in Senegal between June 6 and September 21 2013. The two interventions were compared, with referral to a higher level facility owing to PPH being the outcome measure.