Performance of digital PET/CT compared with conventional PET/CT in oncologic patients: a prospective comparison study.

Purpose: Digital PET systems (dPET) improve lesion detectability as compared to PET systems with conventional photomultiplier tubes (cPET). We prospectively studied the performance of high-resolution digital PET scans in patients with cancer, as compared with high- and standard-resolution conventional PET scans, taking the acquisition order into account.

Methods: We included 212 patients with cancer, who were referred for disease staging or restaging.