Publications by authors named "Aline Sinzervinch"
Article Synopsis
- Aspirin, discovered in 1899 by Felix Hoffman, has been a top-selling drug for 125 years, serving as a major success in the pharmaceutical industry.
- This review highlights various analytical methods used to study Acetylsalicylic Acid (ASA) and their relevance to current sustainable chemistry practices.
- The predominant analytical techniques for ASA are HPLC and UV-Vis, mainly involving traditional solvents like methanol and acetonitrile, suggesting a need for greener solutions in the evaluation of this long-standing medication.
Background: The release of a product in the consumer market requires an analysis by quality control. This sector makes use of reliable analytical methods, by high performance liquid chromatography (HPLC), spectrophotometry in the ultraviolet and visible regions (UV-Vis), spectrophotometry in the infrared region (IR) or thin layer chromatography (TLC), for example, to reach a result. The analysis conditions of most of these analytical methods currently still use toxic reagents, generate a greater amount of waste, sample preparation has more steps, the need for instrumentation and consumables in greater quantity, generating a cost and impact on health and the environment greater than if there were adoption of the Green Analytical Chemistry (GAC) and the White Analytical Chemistry (WAC).
View Article and Find Full Text PDFBackground: Azithromycin (AZT) is an antimicrobial available in different pharmaceutical forms and many people can have access to this medicine. Therefore, the existence of adequate and reliable analytical methods for evaluating the quality of AZT and AZT-based products is essential.
Objective/methods: The purpose of this review is to discuss the analytical methods for evaluating AZT present in the literature and official compendia in the context of Green Analytical Chemistry (GAC).