Congenital Hypothyroidism: Role of Nuclear Medicine.

Thyroid scintigraphy holds a key place in the etiologic workup of neonatal hypothyroidism. Routine screening for this disorder in maternity hospitals in industrialized countries, for nearly 40 years, has permitted early treatment and thereby helped to prevent its physical and mental complications. Neonatal hypothyroidism affects approximately 1 in 3000 births.

Cat-scratch disease and bone scintigraphy.

Cat-scratch disease is a bacterial infection caused by Bartonella henselae. Bone involvement is rare. We describe the case of a 7-year-old boy with a systemic form of the disease.

[Nuclear medicine procedures in paediatric patients].

The paediatricians rely primarily scintigraphic examinations in two situations: when they need functional information to decide operation (measurement of separate function of each kidney for example) or when they want to know if a bone disease is involved, in front of a sudden onset of musculoskeletal disorder. Kidney and bone scan represent 85% of applications for examinations. Some scintigraphic examinations have an essential role in the therapeutic evaluation and staging of malignancies such as MIBG-123 scintigraphy in neuroblastoma and FDG-18F scintigraphy in lymphoma.

Randomized trial of oral versus sequential IV/oral antibiotic for acute pyelonephritis in children.

Objective: To confirm whether oral antibiotic treatment is as efficacious as sequential intravenous/oral antibiotic treatment in the prevention of renal scarring in children with acute pyelonephritis and scintigraphy-documented acute lesions.

Methods: In a prospective multicenter trial, children aged 1 to 36 months with their first case of acute pyelonephritis, a serum procalcitonin concentration ≥0.5 ng/mL, no known uropathy, and a normal ultrasound exam were randomized into 2 treatment groups.

Impressive renal damage after acute pyelonephritis in a child.

Urinary tract infection (UTI) is one of the most common bacterial infections in children, and its role in the pathogenesis of scarred kidney is debated. We report on a 7-year-old child who presented with severe UTI. The early (day 4) renal computed tomography (CT) scan showed normal-sized kidneys (110 mm on the left, 105 mm on the right), whereas the control CT scan and dimercaptosuccinic acid (DMSA) scan, performed 1 and 2 months later, respectively, showed a small scarred right kidney (60 mm) with a 12% residual function.

[To study the safety and effectiveness of heminephroureterectomy by horizontal lumbar posterior approach for duplicated systems in infants].

Purpose: To study the safety and effectiveness of heminephroureterectomy by horizontal lumbar posterior approach for duplicated systems in infants.

Materials And Methods: Thirty-three heminephroureterectomies by lumbar posterior approach were performed in 31 infants at a mean age of 6.7 +/- 5.