Publications by authors named "Aline S E Santos"

Background: Pyrethroids are commonly used insecticides in Brazil. Gestational and early childhood exposure to pyrethroids has been linked to adverse health effects, including neurodevelopmental delays, behavioral issues, and endocrine disruption. This study evaluated the exposure of pregnant women and their children to pyrethroid insecticides in Rio de Janeiro, Brazil.

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Levels of polychlorinated biphenyls (PCB) and organochlorine pesticides (OCP) were evaluated in the breast milk and maternal and umbilical cord blood of pregnant women and their newborns in Rio de Janeiro, Brazil. The concentration of 11 PCB and 17 OCP were measured in 135 samples of maternal, and 116 samples of cord blood plasma, as well as 40, 47, and 45 samples of breast milk at 1st, 3rd, and 6th months after birth, respectively, using gas chromatography-mass spectrometry (GC-MS-MS). Women were asked to answer an enrollment questionnaire with reproductive, lifestyle, residential and sociodemographic questions.

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Article Synopsis
  • Recent research indicates a potential link between pesticide exposure and chronic kidney disease, but its relationship with acute kidney failure (AKF) remains unclear.
  • A study in two Brazilian regions revealed a rise in AKF mortality rates from 1980 to 2014, especially in rural areas with higher pesticide spending.
  • Agricultural workers, particularly younger females in southern regions, showed higher mortality rates from AKF compared to other causes, highlighting the health risks associated with pesticide use in farming.
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Despite evidence from human and animal studies of pesticide immunotoxicity, little is known about the relationship between agricultural pesticide use and autoimmunity. The objective of the present study was to assess the association between pesticide use and anti-cyclic citrullinated peptide (anti-CCP) antibodies and antinuclear antibodies (ANA) levels. A cross-sectional study including healthy 52 agricultural and 68 non-agricultural workers aged 17-69 years was conducted in the Rio de Janeiro State, Brazil.

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Introduction: Mechanics are exposed to known human carcinogens. This study aimed to compare mortality from selected cancers between male mechanics and the general population of the South and Southeast regions of Brazil.

Methods: Data on deaths, occurred between 2006-2017, among male mechanics and the general population, were obtained from the Mortality Information System.

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