Effects of air pollution on clinical pregnancy rates after in vitro fertilisation (IVF): a retrospective cohort study.

Objective: To evaluate the effect of air pollution, from oocyte retrieval to embryo transfer, on the results of in vitro fertilisation (IVF) in terms of clinical pregnancy rates, at two fertility centres, from 2013 to 2019.

Design: Exploratory retrospective cohort study.

Setting: This retrospective cohort study was performed in the Reproductive Biology Department of Bordeaux University Hospital localised in Bordeaux, France and the Jean Villar Fertility Center localised in Bruges, France.

Successful live birth after maturation treatment in a patient with autoimmune premature ovarian failure: a case report and review of the literature.

Objective: We report a successful live birth after oocytes maturation (IVM) and fresh embryo transfer in a patient with autoimmune premature ovarian failure (POF) and performed a review of the literature of livebirths obtained after oocytes IVM treatment in this indication.

Methods: The patient was a 24-year-old woman with autoimmune POF diagnosed post-partum, who developed autoimmune polyglandular syndrome with serum anti-ovarian and anti-21-hydroxylase antibodies. The patient had typical symptoms of POF: secondary amenorrhea with hypoestrogenism, elevated gonadotropins and infertility; however, the serum anti-Müllerian hormone level and total antral follicle count remained normal.

National survey on the opinions of French specialists in assisted reproductive technologies about social issues impacting the future revision of the French Bioethics laws.

Introduction: France is known for its conservative and unique position in assisted reproductive technologies (ARTs). At the eve of the future revision of French Bioethics laws, we decided to conduct a national survey to examine the opinions of French specialists in ARTs about social issues.

Material And Methods: Descriptive study conducted in May 2017 in a university teaching hospital using an anonymous online questionnaire on current issues in ARTs.

Semen and male genital tract characteristics of patients with Fabry disease: the FERTIFABRY multicentre observational study.

Background: Fabry disease (FD) is a rare disorder caused by the deficient activity of α-galactosidase A (α-Gal A). This enzymatic deficit results in the cellular accumulation of globotriaosylceramide (GL-3 or Gb) and related glycosphingolipids in practically all organs and tissues in the body. The identification of deposits of Gb at the reproductive tract level suggests that this part of the body might be involved.

Decrease in pregnancy rate after endometrial scratch in women undergoing a first or second in vitro fertilization. A multicenter randomized controlled trial.

Study Question: Does endometrial scratch in women undergoing a first or second IVF/ICSI attempt improve the clinical pregnancy rate (CPR)?

Summary Answer: Endometrial scratch (ES) in women undergoing their first or second IVF/ICSI attempt does not enhance the CPR under the technical conditions of our study.

What Is Known Already: Several studies have suggested that physical scratch of the endometrium before an IVF attempt could improve embryo implantation.

Study Design, Size, Duration: This was a randomized controlled multi-center, two-arm, parallel trial.

[Method validation of a critical parameter in human embryos culture: culture media pH].

In vitro human embryos culture depends largely on the atmospheric conditions within the incubators of the laboratory. The pH of culture media, an indirect reflection of the CO content inside these incubators, is a critical parameter. Collaboration between the biochemistry and reproductive biology departments enabled the automated measurement of the pH in the culture medium on a blood gas analyzer.

Sperm aneuploidy and DNA fragmentation in unexplained recurrent pregnancy loss: a multicenter case-control study.

Background: Recurrent pregnancy loss (RPL) is defined as the loss of at least three pregnancies in the first trimester. Although the most common cause is embryo aneuploidy, and despite female checkup and couple karyotyping, in about 50% of cases RPL remain unexplained. Male implication has little been investigated and results are discordant.

Sperm cryopreservation in adolescents and young adults with cancer: results of the French national sperm banking network (CECOS).

Objective: To determine the feasibility of fertility preservation in adolescent males with cancer.

Design: Large multicenter retrospective study of male patients ≤20 years from 23 centers of a national network of sperm banks over a 34-year period.

Setting: Sperm banks.

Materno-fetal cardiovascular complications in Turner syndrome after oocyte donation: insufficient prepregnancy screening and pregnancy follow-up are associated with poor outcome.

Context: Recombinant human GH treatment and oocyte donation (OD) have improved the quality of life in women with Turner syndrome (TS). However, life expectancy is reduced, mainly due to cardiovascular complications. Pregnancy may itself increase that risk and be associated with hazardous materno-fetal outcome.

The impact of lymphoma and treatment on male fertility.

Most patients with Hodgkin's or non-Hodgkin's lymphomas will be cured by modern chemotherapy and/or radiotherapy. Although some patients, especially those with Hodgkin's lymphoma, already have semen alterations related to their disease before treatment, sperm damage is mainly caused by anti-cancer treatments. Alkylating and similar drugs and radiation therapy are the most aggressive agents on male gonadal functions.

Azoospermia as a new feature of Fabry disease.

Objective: To describe two cases of azoospermia in men with Fabry disease.

Design: Case report.

Setting: Centre hospitalier universitaire, maternité Pellegrin, Bordeaux, France.

Chlamydia trachomatis in subfertile couples undergoing an in vitro fertilization program: a prospective study.

Objectives: The objectives were to estimate the prevalence of Chlamydia trachomatis infection in subfertile couples and to study the relationship between markers of C. trachomatis infection and male infertility as well as pregnancy rates after in vitro fertilization (IVF).

Study Design: All consecutive couples consulting for infertility and IVF in Pellegrin Hospital were screened for C.

Endometrial vascularity and ongoing pregnancy after IVF.

Background: Embryo transfer is prone to failure.

Aim: To investigate whether endometrial vascularity influences in vitro fertilization (IVF) outcome.

Methods: Total 144 patients receiving IVF (conventional or microinjection) were assessed with color and power Doppler on the day of embryo transfer: age, IVF type, number and quality of embryos, endometrial thickness and aspect, mean uterine PI, uterine notch, type of endometrial vascularity (peripheral or sub- and intra-endometrial), and pregnancy involving second trimester were recorded.