The study explores how three antibiotics (levofloxacin, tetracycline, and benzylpenicillin) adsorb onto silver nanoparticles using techniques like surface-enhanced Raman scattering (SERS) and UV-VIS-NIR spectroscopy.
The researchers used DFT calculations to create theoretical models of the antibiotics for analyzing their vibrational properties and identifying how they bind to the nanoparticles.
The findings indicate the specific functional groups involved in the adsorption for each antibiotic: levofloxacin binds via its carboxylate group, tetracycline through its carbonyl group, and benzylpenicillin via carbonyl moieties from both its carboxylate and amide structures.