Publications by authors named "Aline D do Prado"
Article Synopsis
- The study aimed to assess the quality of referrals for first Rheumatology consultations in Porto Alegre, Brazil, comparing results from a previous survey in 2007/2008 with current findings post-implementation of new referral protocols and teleconsulting systems.
- A total of 357 patient cases were analyzed over a six-month period, recording demographic data and diagnostic suspicions, focusing on the identification of systemic autoimmune inflammatory diseases (SIRD).
- Results showed a significant increase in suspected SIRD diagnoses for both capital and outlying regions, particularly highlighting improved referral quality in areas using the new triage system, indicating positive changes over the past decade.
Background: Imbalance and disfuntion in regulatory T-cells (Tregs) and IL-17 producer lymphocytes (Th17) have been implicated in the pathogenesis of rheumatoid arthritis (RA). Gray scale synovial proliferation (GS), power Doppler signal (pD) and bone erosions seen on high resolution muskuloskeletal ultrasound (MSUS) are hallmarks of destructive articular disease.
Objective: To evaluate the association of peripheral Tregs and Th17 with MSUS findings in RA.
Rheumatoid arthritis (RA) has been associated with early senescent features. However, the effects of disease progression on senescence markers are largely unknown. Here, we evaluated key senescence markers in RA, including telomere length and T cell differentiation stages as well as cytomegalovirus (CMV) serology, previously associated with premature aging.
View Article and Find Full Text PDFHigh-resolution musculoskeletal ultrasound (MSUS) has been increasingly employed in daily rheumatological practice and in clinical research. In rheumatoid arthritis (RA), MSUS can be now considered a complement to physical examination. This method evaluates synovitis through gray-scale and power Doppler and it is also able to identify bone erosions.
View Article and Find Full Text PDFArticle Synopsis
- The article initially had a mistake regarding the spelling of the author's name.
- The incorrect spelling was "José Alexandre de Mendonça."
- The name has now been corrected to "José Alexandre Mendonça" in the updated version.
Ultrasonography (US) is a useful tool for the evaluation of sinovial vascularization and proliferation in rheumatoid arthritis (RA). Accordingly, resistive index (RI) on spectral Doppler (sD) US provides a quantitative analysis of vascular inflammation, but its utility in the evaluation of RA activity has not been established. Our objective was to determine the association of RI with other US parameters of synovitis and with clinical disease activity in established RA.
View Article and Find Full Text PDFThis study aimed to perform an overview of how ultrasound (US) is being used, implemented, and applied in rheumatologic centers in Latin America (LA). A retrospective, multicenter 1-year experience study was undertaken. Eighteen centers from eight countries were involved.
View Article and Find Full Text PDFBackground And Objective: Cytokines have an important role in the pathogenesis of rheumatoid arthritis (RA). Although plasma levels of IL-6 have been related to musculoskeletal ultrasound (MSUS) synovitis in early DMARD-naïve RA, there are no similar studies in established disease.
Methods: 64 RA patients treated with non-biological DMARDs and 30 healthy controls were included in this prospective cross-sectional study.
Introduction: Ultrasonography (US) has a recent use in Rheumatology, and the reliability of the method in rheumatoid arthritis (RA) patients has yet to be clarified.
Objective: To test, in a RA survey, the reproducibility of musculoskeletal US performed by rheumatologists with one-year training through re-analysis by a Rheumatologist experienced in the method.
Patients And Methods: This cross-sectional study included consecutive RA patients from our tertiary center.
Objective: To systematically review the evidence of the association of anticardiolipin antibodies with preeclampsia.
Data Sources: PubMed and LILACS were perused up to June 2009, citations were searched using the ISI Web of Knowledge database, textbooks and reference lists were reviewed, and experts were contacted. Search terms included "antiphospholipid syndrome," "Hughes' syndrome," "anticardiolipin antibodies," "antiphospholipid antibodies," "anti-cardiolipin," "preeclampsia," and "pre-eclampsia.