Publications by authors named "Aline Chiodi Borges"
(1) Background: Previous studies reported the promising inhibitory effect of cold atmospheric plasma (CAP) on . However, the exact mechanisms of CAP's action on the fungal cell are still poorly understood. This study aims to elucidate the CAP effect on cell wall, by evaluating the alterations on its structure and biochemical composition; (2) Methods: cells treated with Helium-CAP were analyzed by atomic force microscopy (AFM) and Fourier transform infrared spectroscopy (FTIR) in order to detect morphological, topographic and biochemical changes in the fungal cell wall.
View Article and Find Full Text PDFDue to the limitations of traditional periodontal therapies, and reported cold atmospheric plasma anti-inflammatory/antimicrobial activities, plasma could be an adjuvant therapy to periodontitis. was grown in blood agar. Standardized suspensions were plated on blood agar and plasma-treated for planktonic growth.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigated how cold atmospheric pressure plasma (CAPP) jet affects the growth, germination, and adherence of the fungus Trichophyton rubrum, which causes nail infections.
- - Laboratory tests showed that exposing T. rubrum to plasma jet for 10 and 15 minutes completely stopped its mycelial growth and significantly reduced its ability to germinate and infect nail samples.
- - Biochemical analysis confirmed these findings, indicating that a single 15-minute exposure to CAPP is a potentially effective treatment for fungal nail infections caused by T. rubrum.
The aim of this study was to establish an effective and safe protocol for in vivo oral candidiasis treatment with atmospheric plasma jets. A novel amplitude-modulated cold atmospheric pressure plasma jet (AM-CAPPJ) device, operating with Helium, was tested. In vitro assays with Candida albicans biofilms and Vero cells were performed in order to determine the effective parameters with low cytotoxicity.
View Article and Find Full Text PDFThe objective of this study was to evaluate the effects of Cymbopogon citratus essential oil and its main compound (citral) against primary dental colonizers and caries-related species. Chemical characterization of the essential oil was performed by gas chromatography/mass spectroscopy (GC/MS), and the main compound was determined. Antimicrobial activity was tested against Actinomyces naeslundii, Lactobacillus acidophilus, S.
View Article and Find Full Text PDFThe aim of this study was to increase the solubility of gallic acid (GA) for the treatment of Candida albicans biofilm, which is very difficult to treat and requires high drug concentrations. Cyclodextrins (CDs) were used for this purpose. Complexes were evaluated by phase-solubility studies, prepared by spray drying and characterized by drug loading, scanning electron microscopy (SEM) and differential scanning calorimetry (DSC).
View Article and Find Full Text PDFAim: This study screened plants for antibacterial properties against bacteria of medical importance.
Materials & Methods: 60 extracts were obtained from the leaves of ten plants (Jatropha weddelliana, Attalea phalerata, Buchenavia tomentosa, Croton doctoris, Mouriri elliptica, Mascagnia benthamiana, Senna aculeata, Unonopis guatterioides, Allagoptera leucocalyx and Bactris glaucescens) using different extraction methods: A) Ethanol 70°C/72 h; B) Water/5 min/100°C; C) Water/1 h/55°C; D) Water/72 h; E) Hexane/72 h and F) Ethanol 99°C/72 h. Enterobacteria/Pseudomonas and staphylococci reference strains and 201 clinical isolates were used.