Burden of adult neurofibromatosis 1: development and validation of a burden assessment tool.

Background: Neurofibromatosis Type 1 (NF1) is a common genetic neurocutaneous disease, with an autosomal dominant inheritance mode. Quality of life has been shown impaired in NF1, due to severe complications, cosmetic features, and uncertainty about the disorder.

Methods: This study sought to develop a self-administered questionnaire in French to assess the burden of NF1 (BoN), then translate and linguistically and cross-culturally validate it into American English, standardized methodology applied, as outlined in the report.

Outcome evaluation in shoulder surgery using 3D kinematics sensors.

A new method of scoring systems for the functional assessment of the shoulder is presented. 3D accelerometers and gyroscopes attached on the humerus were used to differentiate a healthy from a painful shoulder. The method was first tested on 10 healthy volunteer subjects with no shoulder pathology.

[Predonation of autologous blood in knee arthroplasty].

During knee arthroplasty, autologous blood donation is frequently used as an alternative to homologous blood transfusion. The hemoglobin level determines the organism answer to the anemia induced by the iteratives phlebotomies. We reviewed retrospectively 140 patients to correlate the hemoglobin levels before the predonations, pre- and postoperatively.