Publications by authors named "Alina Musetescu"

Background/objectives: This study examines the perception of young Romanians (aged 18-35) regarding the Ukraine conflict's impact on Romania's national security and quality of life. It focuses on societal security dimensions, analyzing the conflict's regional and international implications, alongside sentiments toward global support for Ukraine.

Methods: Data were collected via structured questionnaires administered to 848 participants in 2024 and 747 in 2022.

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Article Synopsis
  • - The study examines Romanian pharmacists' views on self-medication, emphasizing its impact on public health and the importance of pharmacist involvement in educating patients about proper medicine use.
  • - Researchers distributed a questionnaire to 300 pharmacists across Romania, using statistical methods to analyze the data and find connections between self-medication habits and various factors.
  • - Results suggest that self-medication is more common for minor health issues, and pharmacists with more experience are less prone to support it; education campaigns can help mitigate risks related to self-medication practices.
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Article Synopsis
  • Psoriasis is a common inflammatory skin disease that poses challenges in treatment, making topical therapies an attractive option due to their better patient compliance and fewer systemic side effects.
  • Numerous new and improved substances for topical application are being explored, including natural compounds like lycopene and synthetic options like siRNAs, with research focusing on their effectiveness in animal models.
  • Recent studies emphasize the significance of animal research in dermatology, highlighting the development of advanced delivery systems like vesicular systems to enhance the efficacy of topical treatments for psoriasis.
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Antimicrobial peptides (AMPs) are a group of oligopeptides found in most multicellular organisms with a capacity for rapid and nonspecific destruction of pathogens. The action of destroying pathogens is associated with a strong proinflammatory activity, stimulating the secretion of cytokines, chemokines, growth factors but also chemotaxis, the activation of dendritic cells and involving adaptive immunity also. The action of AMPs fits perfectly into the characteristics of innate immunity which makes these peptides candidates to be considered as an important element of this type of immunity.

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Cutaneous symptoms are characteristic for the autoinflammatory disorders (AIDs), both in the classical autoinflammatory phenotype and in most disorders included in this syndrome, but they are not specific and inconstant. Several skin disorders (pyoderma gangrenosum and pustular acne) may be encountered either isolate or associated with autoinflammatory symptoms, forming well-defined clinical entities within the autoinflammatory syndrome. The high prevalence of cutaneous manifestations is an important characteristic of AIDs.

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