CERAD-NAB and flexible battery based neuropsychological differentiation of Alzheimer's dementia and depression using machine learning approaches.

Depression (DEP) and dementia of the Alzheimer's type (DAT) represent the most common neuropsychiatric disorders in elderly patients. Accurate differential diagnosis is indispensable to ensure appropriate treatment. However, DEP can yet mimic cognitive symptoms of DAT and patients with DAT often also present with depressive symptoms, impeding correct diagnosis.

Differential Linguistic Recall Effects in the California Verbal Learning Test in Healthy Aging and Alzheimer's Dementia: Analysis of Routine Diagnostic Data.

Objective: Psycholinguistic evidence suggests that certain word characteristics might influence recall rates in word-list learning tests. These effects were investigated in the German California Verbal Learning Test (CVLT-G) in a clinical setting.

Method: Subjects were memory clinic patients without cognitive diagnosis (N = 45) and with dementia of the Alzheimer type (DAT) (N = 48) matched for age, sex, depressive symptoms, and education.