Absence of erythrocyte sequestration in a case of babesiosis in a splenectomized human patient.

Background: The importance of vascular occlusion in the pathogenesis of human haemoprotozoal disease is unresolved.

Methods: Giemsa-stained tissue sections from a human case of Babesia microti infection in a splenectomized patient with chronic lymphocytic leukaemia and colon cancer were examined to ascertain the distribution of parasitized erythrocytes within the vascular lumen.

Results: No evidence of sequestration was observed.

Immunohistochemical localization of the retinoic Acid receptors in human prostate.

Retinoic acid receptors (RARs) are nuclear transcription factors that mediate the effects of retinoids. Aberrant expression and regulation of RARs have been linked to various malignancies, including steroid-related breast and cervical cancers. Our previous results also suggest that prostate cancer is associated with altered RAR signaling.

A comparison of prognostic tumor markers obtained on image-guided breast biopsies and final surgical specimens.

Background: This study was initiated to determine whether tumor markers obtained on image-guided breast biopsy specimens provide accurate prognostic information for women with invasive breast cancer.

Methods: Prognostic tumor markers on preoperative image-guided biopsy and final surgical specimens were compared in 44 patients with invasive breast cancer.

Results: Progesterone receptor (PR) discordance was 18%.