Polyurethane/β-cyclodextrin/ciprofloxacin composite films for possible medical coatings with antibacterial properties.

Polyurethane/β-cyclodextrin/ciprofloxacin composite films have been prepared and structural and morphological behaviours reveal the progressive incorporation of the drug ciprofloxacin into polyurethane backbones. Spectral changes such as frequency shifts, band broadening and changes in the intensity are indicative of drug-polyurethane interactions. X-ray powder diffraction experiments demonstrate that ciprofloxacin retains its crystallinity in the polyurethane matrix.