Burnout Syndrome in forensic medicine and its association with vicarious trauma, posttraumatic stress syndrome and occupational stress.

The burnout phenomenon is a subject of considerable interest due to its impact on both employee well-being and scientific inquiry. Workplace factors, both intrinsic and extrinsic, play a pivotal role in its development, often leading to job dissatisfaction and heightened burnout risk. Chronic stress and burnout induce significant dysregulation in the autonomic nervous system and hormonal pathways, alongside structural brain changes.

Carbonic anhydrase inhibitors. Inhibition of human cytosolic isoforms I and II with (reduced) Schiff's bases incorporating sulfonamide, carboxylate and carboxymethyl moieties.

A library of Schiff bases was synthesized by condensation of aromatic amines incorporating sulfonamide, carboxylic acid or carboxymethyl functionalities as Zn(2+)-binding groups, with aromatic aldehydes incorporating tert-butyl, hydroxy and/or methoxy groups. The corresponding amines were thereafter obtained by reduction of the imines. These compounds were assayed for the inhibition of two cytosolic human carbonic anhydrase (hCA, EC 4.

Polyurethane/β-cyclodextrin/ciprofloxacin composite films for possible medical coatings with antibacterial properties.

Polyurethane/β-cyclodextrin/ciprofloxacin composite films have been prepared and structural and morphological behaviours reveal the progressive incorporation of the drug ciprofloxacin into polyurethane backbones. Spectral changes such as frequency shifts, band broadening and changes in the intensity are indicative of drug-polyurethane interactions. X-ray powder diffraction experiments demonstrate that ciprofloxacin retains its crystallinity in the polyurethane matrix.

Conservative treatment of dental trauma: case presentation-direct adhesive restoration techniques of the 4 upper incisors with different types of fractures on the coronal level.

Dental trauma creates serious functional, aesthetic and psychological problems for the patient. The known developments in recent years in the area of materials and techniques related to direct composite resin restorations provide for the dentists direct conservative solutions that allow both morphology and aesthetic restoration and preservation of pulp vitality in many of the clinical situations encountered. A careful clinical examination and an accurate diagnosis (in terms of classification of the trauma) will allow the dentist to choose the most conservative therapeutic solution.