The natural history of congenital hypothyroidism with delayed TSH elevation in neonatal intensive care newborns.

Objective: To assess the clinical and neurological outcomes in newborns with primary congenital hypothyroidism presented with delayed TSH elevation (dTSH), and to define parameters that may predict the evolution of transient vs. permanent hypothyroidism in these newborns.

Design And Patients: An observational study was performed of a cohort of 113 children with a history of dTSH.