Introduction And Importance: Acinic cell carcinoma (AciCC) is a rare entity in which high-grade transformation (HGT), formerly dedifferentiation, is uncommon. This case report presents a rare case of AciCC, with rapid transformation to metastatic high-grade dedifferentiated pathology after initial curative treatment.
Case Presentation: A 58-year-old woman presented in the medical oncology clinic with a progressive swelling on the right side of her face.