Publications by authors named "Aligbe O"
It is unknown if recurrent urinary tract infection in the gynecologic population is associated with Mycoplasma and Ureaplasma genitourinary infections. The purpose of this scoping review is to highlight the literature surrounding Mycoplasma and Ureaplasma infections in the setting of recurrent urinary tract infections in the gynecologic population. MEDLINE ALL and Embase were searched to retrieve articles published in or after 1950 through 2024.
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- Chronic kidney disease often leads to severe anemia and iron deficiency due to factors like low erythropoietin production, iron deficiency, and inflammation, which is typically treated with synthetic erythropoietin injections.
- High levels of fibroblast growth factor 23 (FGF23) in kidney disease have been linked to reduced red blood cell production and exacerbated anemia.
- Inhibiting FGF23 signaling not only stimulates red blood cell production and alleviates anemia but also reduces inflammation and increases iron levels, presenting a potential new treatment approach for improving patient outcomes in chronic kidney disease.
Wntless (Wls) transports Wnt molecules for secretion; however, the cellular mechanism underlying the initial assembly of Wnt secretory vesicles is still not fully defined. Here, we performed proteomic and mutagenic analyses of mammalian Wls, and report a mechanism for formation of early Wnt secretory vesicles on ER membrane. Wls forms a complex with SEC12 (also known as PREB), an ER membrane-localized guanine nucleotide-exchange factor (GEF) activator of the SAR1 (the SAR1A isoform) small GTPase.
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